Role of systems pharmacology in understanding drug adverse events
نویسندگان
چکیده
منابع مشابه
Choosing appropriate theories for understanding hospital reporting of adverse drug events, a theoretical domains framework approach
Adverse drug events (ADEs) may cause serious injuries including death. Spontaneous reporting of ADEs plays a great role in detection and prevention of them, however, underreporting always exists. Although several interventions have been utilized to solve this problem, they are mainly based on experience and the rationale for choosing them has no theoretical base. The vast variety of behavioral ...
متن کاملChoosing appropriate theories for understanding hospital reporting of adverse drug events, a theoretical domains framework approach
Adverse drug events (ADEs) may cause serious injuries including death. Spontaneous reporting of ADEs plays a great role in detection and prevention of them, however, underreporting always exists. Although several interventions have been utilized to solve this problem, they are mainly based on experience and the rationale for choosing them has no theoretical base. The vast variety of behavioral ...
متن کاملSystems analysis of adverse drug events.
Objective.\p=m-\To identify and evaluate the systems failures that underlie errors causing adverse drug events (ADEs) and potential ADEs. Design.\p=m-\Systemsanalysis of events from a prospective cohort study. Participants.\p=m-\Alladmissions to 11 medical and surgical units in two tertiary care hospitals over a 6-month period. Main Outcome Measures.\p=m-\Errors,proximal causes, and systems fai...
متن کاملUnderstanding adverse events: human factors.
(1) Human rather than technical failures now represent the greatest threat to complex and potentially hazardous systems. This includes healthcare systems. (2) Managing the human risks will never be 100% effective. Human fallibility can be moderated, but it cannot be eliminated. (3) Different error types have different underlying mechanisms, occur in different parts of the organisation, and requ...
متن کاملAnticoagulation-associated adverse drug events.
PURPOSE Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. METHODS We reviewed all inpatient anticoagulant-associated ADEs, including adverse dr...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: Systems Biology and Medicine
سال: 2010
ISSN: 1939-5094
DOI: 10.1002/wsbm.114